Meitantei Holmes - M Kara no Chousenjou, translating to "Detective Holmes - The Challenge from M," is a Japanese NES game from the Sherlock Holmes franchise. It's another mystery game probably involving detective work, puzzle solving and investigation. Gameplay will likely involve exploring environments, gathering clues, and solving the mystery presented by "M."  Additional details about the developer and release date need further research.

Meitantei Holmes - M Kara no Chousenjou (Japan)

Meimon! Dai San Yakyuu Bu (Japan)