Best of the Best: Championship Karate is a fighting game released for the Sega Genesis. The European and US releases likely shared similar gameplay, with players choosing a character and engaging in one-on-one karate combat.  The game likely featured various moves, special attacks, and potentially different game modes, standard for the genre at the time.  Specific details about each region's release may have differed slightly in terms of features or presentation.

Best of the Best - Championship Karate (Europe)

Beethoven's 2nd - The Quest for Pups (prototype)